• • DRAMP ID

  • DRAMP39388

• • Peptide Name

  • Peptide 10

• • Source

  • Synthetic construct

• • Family

  • Flaviviridae

• • Gene

  • Not found

• • Sequence

  • SPRTGLDFNEMI

• • Sequence Length

  • 12

• • UniProt Entry

• • Protein Existence

  • Not found

• • SMILES

  • CC[C@@H](C)[C@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(C)=O)[C@@H](C)O)C(N)=O

• • Biological Activity

  • [Ref.36739680]Peptide 10 (200 μM) exhibited inhibitions of all four DENV serotypes, with high inhibitions of DENV-4 at 81.13%, followed by DENV-3 at 60.47% and DENV-1 at 47.01%.

• • Target Organism

  • DENV

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not found

• • Binding Target

  • plasma membrane

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Acetylation

• • C-terminal Modification

  • Amidation

• • Nonterminal Modifications and Unusual Amino Acids

  • Not found

• • Stereochemistry

  • L

• • Structure

• • Structure Description

• • PDB ID

• Predicted Structure

• There is no predicted structure for DRAMP39388.

DRAMP39388

• ·Literature 1

• • Title

  • Development of novel antiviral peptides against dengue serotypes 1-4. 

• • Pubmed ID

  • 36739680

• • Reference

  • Virology. 2023 Mar;580:10-27.

• • Author

  • Lee MF, Anasir MI, Poh CL.