• • DRAMP ID

  • DRAMP39389

• • Peptide Name

  • Peptide 11

• • Source

  • Synthetic

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • TNTTT

• • Sequence Length

  • 5

• • UniProt Entry

  • Notfound

• • Protein Existence

  • Not found

• • SMILES

  • CC(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(N)=O)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O

• • Biological Activity

  • [Ref.36739680]Peptides 11 at 200 μM exhibited cell protection effects below 50% against all four DENV serotypes(DENV-1, DENV-2, DENV-3, DENV-4); peptides 11 (200 μM) also showed inhibitions of all fou

• • Target Organism

  • • [Ref.26039561]protozoon: P. falciparum(75% inhibition at 100μM)

• • Hemolytic Activity

  • • [Ref.26039561]Non-haemolytic at 10μM concentration

• • Cytotoxicity

  • • Not found

• • Binding Target

  • plasma membrane

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • palmitoylation

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

  • Not found

• • Stereochemistry

  • L

• • Structure

• • Structure Description

• • PDB ID

  • Notfound

• Predicted Structure

• There is no predicted structure for DRAMP39389.

DRAMP39389

• ·Literature 1

• • Title

  • Design and evaluation of antimalarial peptides derived from prediction of short linear motifs in proteins related to erythrocyte invasion.

• • Pubmed ID

  • 26039561

• • Reference

  • PLoS One. 2015 Jun 3;10(6):e0127383.

• • Author

  • Bianchin A, Bell A, Chubb AJ, Doolan N, Leneghan D, Stavropoulos I, Shields DC, Mooney C.