• • DRAMP ID

  • DRAMP39390

• • Peptide Name

  • Peptide 12

• • Source

  • Synthetic construct

• • Family

  • Flaviviridae

• • Gene

  • Not found

• • Sequence

  • DANFV

• • Sequence Length

  • 5

• • UniProt Entry

• • Protein Existence

  • Not found

• • SMILES

  • CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(N)=O)C(C)C

• • Biological Activity

  • [Ref.36739680]Peptides 12 at 200 μM exhibited cell protection effects below 50% against all four DENV serotypes(DENV-1, DENV-2, DENV-3, DENV-4); peptide 12 (200 μM) also showed inhibitions of all four

• • Target Organism

  • DENV

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not found

• • Binding Target

  • plasma membrane

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Acetylation

• • C-terminal Modification

  • Amidation

• • Nonterminal Modifications and Unusual Amino Acids

  • Not found

• • Stereochemistry

  • L

• • Structure

• • Structure Description

• • PDB ID

• Predicted Structure

• There is no predicted structure for DRAMP39390.

DRAMP39390

• ·Literature 1

• • Title

  • Development of novel antiviral peptides against dengue serotypes 1-4. 

• • Pubmed ID

  • 36739680

• • Reference

  • Virology. 2023 Mar;580:10-27.

• • Author

  • Lee MF, Anasir MI, Poh CL.