• • DRAMP ID

  • DRAMP39396

• • Peptide Name

  • HRP IIC

• • Source

  • Synthetic

• • Family

  • not found

• • Gene

  • not found

• • Sequence

  • CGAHHAADAHHAADAHHAADGC

• • Sequence Length

  • 22

• • UniProt Entry

  • notfound

• • Protein Existence

  • not found

• • SMILES

  • C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](C)C(=O)NCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CS)C(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](N)CS)C(=O)O

• • Biological Activity

  • Antimicrobial, Antiprotozoal

• • Target Organism

  • • [Ref.9497049]protozoon: Plasmodium yoelii(40-50% inhibition of haem polymerization activity at 100 µM)

• • Hemolytic Activity

  • • not found

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

• • Stereochemistry

  • L

• • Structure

• • Structure Description

• • PDB ID

  • notfound

• Predicted Structure

• There is no predicted structure for DRAMP39396.

DRAMP39396

• ·Literature 1

• • Title

  • Synthetic peptides corresponding to a repetitive sequence of malarial histidine rich protein bind haem and inhibit haemozoin formation in vitro.

• • Pubmed ID

  • 9497049

• • Reference

  • Mol Biochem Parasitol. 1997 Dec 1;90(1):281-7

• • Author

  • Pandey AV, Joshi R, Tekwani BL, Singh RL, Chauhan VS