• DRAMP ID

    • DRAMP39406
    • Peptide Name

    • Cyclo(Phe–Phe)
    • Source

    • Synthetic
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • FF
    • Sequence Length

    • 2
    • UniProt Entry

    • Protein Existence

    • Not found
    • SMILES

    • Not available
    • Biological Activity

    • Antimicrobial, Antiprotozoal
    • Target Organism

      • [Ref.23084276]protozoon: P. berghei schizonts(IC50=2.54µM)
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not found
    • Binding Target

    • binding sites of enzymes and proteins
    • Linear/Cyclic

    • Cyclic
    • N-terminal Modification

    • Cyclization (N termini to C termini)
    • C-terminal Modification

    • Cyclization (C termini to N termini)
    • Nonterminal Modifications and Unusual Amino Acids

    • Not found
    • Stereochemistry

    • L
    • Structure

    • Structure Description

    • Predicted Structure

    • There is no predicted structure for DRAMP39406.
    • Formula

    • C18H20N2O3
    • Absent Amino Acids

    • Ala,Cys,Asp,Glu,G
    • Common Amino Acids

    • Phe
    • Mass

    • 312.36
    • PI

    • 5.53
    • Basic Residues

    • 0
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 2
    • Net Charge

    • 0
    • Boman Index

    • 0
    • Hydrophobicity

    • 0.028
    • Aliphatic Index

    • 0
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 0

DRAMP39406

  • ·Literature 1
    • Title

    • Linear and cyclic dipeptides with antimalarial activity.
    • Reference

    • Bioorg Med Chem Lett. 2012 Dec 1;22(23):7048-51.
    • Author

    • Pérez-Picaso L, Olivo HF, Argotte-Ramos R, Rodríguez-Gutiérrez M, Rios MY.