General Information
-
DRAMP ID
- DRAMP39545
-
Peptide Name
- bsa094_6
-
Source
- Synthetic construct
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- GLWSKAKETGKEAAKAAAKAAGKAALGAVSEAL
-
Sequence Length
- 33
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
-
SMILES
- Not available
Activity Information
-
Biological Activity
- No significant antimicrobial activity
-
Target Organism
-
- [Ref.40906555]Gram-negative bacteria:
Target Organism Activity E. coli ATCC 25922 MIC=250 μg/mL
- [Ref.40906555]Gram-negative bacteria:
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
- No cytotoxicity information found in the reference(s) presented
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Linear
-
N-terminal Modification
- Free
-
C-terminal Modification
- Free
-
Nonterminal Modifications and Unusual Amino Acids
- None
-
Stereochemistry
- L
-
Structure
- Not found
-
Structure Description
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP39545.
Physicochemical Information
-
Formula
- C139H236N40O43
Absent Amino Acids
- Cys,Asp,Phe,His,I
Common Amino Acids
- Ala,Glu,G
Mass
- 3155.6
PI
- 9.7
Basic Residues
- 6
Acidic Residues
- 3
Hydrophobic Residues
- 17
Net Charge
- +3
-
Boman Index
- 0
Hydrophobicity
- -0
Aliphatic Index
- 80.61
Half Life
-
- Mammalian:30 hours
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 5500
Absorbance 280nm
- 1.74
Polar Residues
- 3
DRAMP39545
Comments Information
Literature Information
- ·Literature 1
-
Title
- EBAMP: An efficient de novo broad-spectrum antimicrobial peptide discovery framework.
-
Pubmed ID
- 40906555
-
Reference
- Cell Rep. 2025 Sep 23;44(9):116215.
-
Author
- Zhao Y, Li Q, Sun M, Su Y, Su X, Jiang L, Zhang X, Hu Y, Wang B, Yu H, Zhang Q, Chai Z, Yao D, Ren Y, Huang W, Jin Y, Dou Y, Li D, Huang Z, Liu P, Ren H, Jiang Y.
