General Information

    • DRAMP ID

    • DRAMP37309

    • Peptide Name

    • KL-21(Primary structure based on Mastoparan and Cecropin A)

    • Source

    • Sythetic

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • KWKLFKKINWKKIGAVVKKIL

    • Sequence Length

    • 21

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial,Anti-Gram-

    • Target Organism

      • Gram-positive bacteria:listeria monocytogenes，ATCC 19115 (MIC=16.0 µM)
      • Gram-negative bacteria: Salmonella Paratyphi B CMCC 50094 (MIC=32.0 µM), Pseudomonas aeruginosa CMCC 10104 (MIC=16.0 µM)
      • Fungus: Candida albicans，CMCC 98001 (MIC=16.0 µM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented

    • Binding Target

    • Cell membrane

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • Free

    • C-terminal Modification

    • Free

    • Nonterminal Modifications and Unusual Amino Acids

    • None

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Predicted Structure

    • There is no predicted structure for DRAMP37309.

Literature Information

  • ·Literature 1

    • Title

    • 杂合抗菌肽KL-21与抗生素体外协同抗菌效果研究：Research on Synergistic Antibacterial Effect of Hybrid Antimicrobial Peptide KL-21 and Antibiotics In Vitro

    • doi

    • 10.13302/j.cnki.fi.2024.12.018.

    • Reference

    • [J/OL].饲料工业:1-7[2024-03-18].

    • Author

    • 韩晋辉,翟培,吕文平： HAN Jinhui ZHAI Pei LYU Wenping LI Routing LIN Jin