Patent Information

    • DRAMP ID

    • DRAMP38949

    • Sequence

    • GIGVTQNVLYENQKQIANQF

    • Sequence Length

    • 20

    • Sequence Name

    • SEQ ID NO:9

    • Source

    • Synthetic construct

    • SMILES

    • Not available

    • Activity

    • Antimrobial; Antiviral

    • Patent Type

    • Granted Patent

    • Publication Date

    • 2009-2-17

    • Patent Title

    • Synthetic peptide targeting critical sites on the SARS-associated coronavirus spike protein responsible for viral infection and method of use

    • Abstract

    • The present invention provides methods for locating critical portions or sites on the spike protein (S protein) of SARS-associated coronavirus (SARS-CoV) responsible for the viral infection that causes Severe Acute Respiratory Syndrome (SARS). The present invention also provides new synthetic peptides targeting such critical portions or sites of the S protein of SARS-CoV for preventing or treating of SARS-CoV infection in a subject. The present invention further provides methods of testing antiviral activity exerted by antiviral agents using real-time quantitative PCR.