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Sequence
- PALNCYWPLNDYGFYTTSGI
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Sequence Name
- SEQ ID NO:4
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Source
- Synthetic construct
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Activity
- Antimrobial; Antiviral
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Patent Type
- Granted Patent
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Publication Date
- 2009-2-23
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Patent Title
- Synthetic peptide targeting critical sites on the SARS-associated coronavirus spike protein responsible for viral infection and method of use
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Abstract
- The present invention provides methods for locating critical portions or sites on the spike protein (S protein) of SARS-associated coronavirus (SARS-CoV) responsible for the viral infection that causes Severe Acute Respiratory Syndrome (SARS). The present invention also provides new synthetic peptides targeting such critical portions or sites of the S protein of SARS-CoV for preventing or treating of SARS-CoV infection in a subject. The present invention further provides methods of testing antiviral activity exerted by antiviral agents using real-time quantitative PCR.