General Information

    • DRAMP ID

    • DRAMP00240

    • Peptide Name

    • Pep27 (Bacteriocin)

    • Source

    • Streptococcus pneumoniae (Gram-negative bacteria)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • MRKEFHNVLSSGQLLADKRPARDYNRK

    • Sequence Length

    • 27

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antibacterial, Anti-cancer, Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00240 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00240.

Physicochemical Information

    • Formula

    • C139H229N47O40S

    • Absent Amino Acids

    • CITW

    • Common Amino Acids

    • R

    • Mass

    • 3230.7

    • PI

    • 10.42

    • Basic Residues

    • 8

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 7

    • Net Charge

    • +5

    • Boman Index

    • -102.31

    • Hydrophobicity

    • -1.293

    • Aliphatic Index

    • 61.48

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 57.31

    • Polar Residues

    • 6

DRAMP00240

DRAMP00240 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Functional and structural characteristics of Anti-cancer peptide Pep27 analogues.

    • Reference

    • Cancer Cell Int. 2005 Jul 11;5:21.

    • Author

    • Lee DG, Hahm KS, Park Y, Kim HY, Lee W, Lim SC, Seo YK, Choi CH.