Clinical-Browse

Result: 1 - 20 of 76

DownLoad :

FASTA

HTML

XLS

XML

DRAMP ID	NAME	Description	Medical_use	Stage of development	Company
DRAMP18057	MSI-78(Pexiganan)	a broad-spectrum synthetic analogue of the African frog peptide magainin	impetigo	Phase III(Failure)	Genaera (Plymouth, PA)
DRAMP18058	MSI-78(Pexiganan)	a broad-spectrum synthetic analogue of the African frog peptide magainin	treatment of diabetic foot ulcers	Phase III(denied approval for use in 1999	Genaera (Plymouth, PA)
DRAMP18059	Iseganan(IB-367)	a synthetic analogue of Protegrin I (IBL-367),extracted from porcine leukocytes;the pig protegrin derivative	a mouth rinse to prevent polymicrobial infection associated with oral mucositis in patients receiving chemotherapy	Phase III(Failure)	Intrabiotics Pharmaceuticals Inc.(Mountain View, CA)
DRAMP18060	Iseganan(IB-367)	a synthetic analogue of Protegrin I (IBL-367),extracted from porcine leukocytes;the pig protegrin derivative	an aerosolized treatment for ventilator-associated pneumonia	Phase III(Failure)	Intrabiotics Pharmaceuticals Inc.(Mountain View, CA)
DRAMP18061	Histatin	using a variant of histatins, which are naturally occurring cationic peptides in saliva	antimicrobial-peptide-containing mouth wash for the treatment of oral candidiasis (gingivitis and periodontal diseases)	Phase II-III	Demgen and Dow Pharmaceutical Sciences;licensed to the Vancouver, Canada, company Pacgen
DRAMP18062	Histatin	using a variant of histatins, which are naturally occurring cationic peptides in saliva	chronic Pseudomonas aeruginosa infections	Phase I	Demgen and Dow Pharmaceutical Sciences;licensed to the Vancouver, Canada, company Pacgen
DRAMP18063	P113	a 12 amino acid fragment of histatin 5	HIV	Phase II(Completed)	Demgen
DRAMP18064	P113D	a 12 amino acid fragment of histatin 5	an inhalation treatment for Pseudomonas aeruginosainfections in cystic fibrosis patients	Unknow	Demgen
DRAMP18065	MBI-226(Omiganin)	Synthetic 12-mer cationic peptide derived from indolicidin	the treatment of catheter-related infections	Phase IIIb(Failure)	Migenix (Vancouver, BritishColumbia, Canada)
DRAMP18066	MBI peptides as Omiganan(particularly MBI-226 and M	analogues of indolicidin	acne and chronic nasal carrier of S. aureus	Phase II(Failure)	Migenix (Vancouver, BritishColumbia, Canada)
DRAMP18067	MX-594AN	Indolicidin based	the treatment of catheter-related acne	Phase IIb(Completed)	Migenix (Vancouver, BritishColumbia, Canada)
DRAMP18068	hLF1-11	an 11-mer peptide from the N terminus of human lactoferrin	LPS-mediated diseasesand fungal infections	Phase I(Completed)	AM-Pharma Holding BV
DRAMP18069	rBPI21(Neuprex)	a human bactericidal permeability protein derivative	meningococcaemia;prophylactic treatment of infectious complications from post-traumatic bleeding (in 842 patients)	Phase III(Failure)	Xoma Ltd(Berkeley, CA, USA)
DRAMP18070	XMP 629	extracted from human	Acne	Phase III	Xoma Ltd(Berkeley, CA, USA)
DRAMP18071	Mycoprex	extracted from insects	Fungal infections	Phase III	Xoma Ltd.
DRAMP18072	Heliomocin variants(ETD151)	an antifungal 44 amino acid peptide, variant of a natural peptide from lepidopteran Heliothis virescens	Systemic fungal infections in immunocompromised patients and multi-resistant bacterial infections	Preclinical	EntoMed SA
DRAMP18073	PG-1	Protegrin Class	Treatment of peritoneal infections caused by P. aeruginosa and S. aureus.Treatment of pneumonia	Unknow	Intrabiotics
DRAMP18074	CSA-13	cationic steroid (ceragenin) that mimics host-defense peptides	Anti-infective	Preclinical	Ceragenix(Denver)
DRAMP18075	HB-50	synthetic natural peptide mimetic of cecropin	Anti-infective	Preclinical	Helix Biomedix(Bothell, Washington, USA)
DRAMP18076	HB-107	19-amino-acid fragment of cecropin B	Wound healing	Preclinical	Helix Biomedix(Bothell, Washington, USA)