General Information
-
DRAMP ID
- DRAMP03551
-
Peptide Name
- Adrenomedullin (Human, mammals, animals)
-
Source
- Homo sapiens (Human)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- YRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGY
-
Sequence Length
- 52
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Not found
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- 2L7S
-
Predicted Structure
- There is no predicted structure for DRAMP03551.
Physicochemical Information
-
Formula
- C264H407N79O78S3
Absent Amino Acids
- EW
Common Amino Acids
- Q
Mass
- 6031.8
PI
- 9.7
Basic Residues
- 9
Acidic Residues
- 3
Hydrophobic Residues
- 12
Net Charge
- +6
-
Boman Index
- -135.62
Hydrophobicity
- -0.887
Aliphatic Index
- 45
Half Life
-
- Mammalian:2.8 hour
- Yeast:10 min
- E.coli:2 min
Extinction Coefficient Cystines
- 4595
Absorbance 280nm
- 90.1
Polar Residues
- 19
DRAMP03551
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- An investigation into the antimicrobial effects of adrenomedullin on members of the skin, oral, respiratory tract and gut microflora.
-
Pubmed ID
- 10225288
-
Reference
- FEMS Immunol Med Microbiol. 1999 Apr;23(4):289-293.
-
Author
- Allaker RP, Zihni C, Kapas S.