General Information

    • DRAMP ID

    • DRAMP03562

    • Peptide Name

    • P1 (Human, mammals, animals)

    • Source

    • Homo sapiens (Human)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FLAKAVAKAAAKALAKAL

    • Sequence Length

    • 18

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • Yeast: Candida albicans (MIC=82 µM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • Free

    • C-terminal Modification

    • Amidation

    • Nonterminal Modifications and Unusual Amino Acids

    • Free

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03562 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03562.

Physicochemical Information

    • Formula

    • C83H146N22O19

    • Absent Amino Acids

    • CDEGHIMNPQRSTWY

    • Common Amino Acids

    • A

    • Mass

    • 1756.21

    • PI

    • 10.48

    • Basic Residues

    • 4

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 14

    • Net Charge

    • +4

    • Boman Index

    • 15.87

    • Hydrophobicity

    • 1.056

    • Aliphatic Index

    • 131.11

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 0

DRAMP03562

DRAMP03562 chydropathy plot

Comments Information

    • Function

    • Presentes antifungal activity against Candida albicans.

Literature Information

  • ·Literature 1

    • Title

    • Predicting antimicrobial peptides from eukaryotic genomes: In silico strategies to develop antibiotics.

    • Reference

    • Peptides. 2012 Oct;37(2):301-308.

    • Author

    • Amaral AC, Silva ON, Mundim NC, de Carvalho MJ, Migliolo L, Leite JR, Prates MV, Bocca AL, Franco OL, Felipe MS.