General Information

    • DRAMP ID

    • DRAMP00744

    • Peptide Name

    • Putative defensin-like protein 315 (Plant defensin)

    • Source

    • Arabidopsis thaliana (Mouse-ear cress)

    • Family

    • Belongs to the DEFL family

    • Gene

    • Not found

    • Sequence

    • MYLSSRTGSRLLFLVKASFNTFEKVATISSTLIYFVSHKLVSSRSCSHNFRNICGYIRHNCRKCIRFCFCTFSIKISLPLVIARRIEY

    • Sequence Length

    • 88

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00744 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00744.

Physicochemical Information

    • Formula

    • C463H736N130O119S7

    • Absent Amino Acids

    • DQW

    • Common Amino Acids

    • S

    • Mass

    • 10252.16

    • PI

    • 10.15

    • Basic Residues

    • 17

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 33

    • Net Charge

    • +15

    • Boman Index

    • -128.78

    • Hydrophobicity

    • 0.278

    • Aliphatic Index

    • 95.23

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 6335

    • Absorbance 280nm

    • 72.82

    • Polar Residues

    • 34

DRAMP00744

DRAMP00744 chydropathy plot

Comments Information

    • PTM

    • Contains two disulfide bonds (By similarity).

    • Caution

    • Could be the product of a pseudogene. Lacks the signal peptide and 2 of the 4 disulfide bonds, which are conserved features of the family.

Literature Information

  • ·Literature 1

    • Title

    • Genome organization of more than 300 defensin-like genes in Arabidopsis.

    • Reference

    • Plant Physiol. 2005 Jun;138(2):600-610.

    • Author

    • Silverstein KA, Graham MA, Paape TD, VandenBosch KA.