General Information
-
DRAMP ID
- DRAMP00751
-
Peptide Name
- Defensin-2 (Plant defensin)
-
Source
- Pinus sylvestris (Scots pine)
-
Family
- Belongs to the DEFL family
-
Gene
- Def2
-
Sequence
- RMCKTPSAKFKGYCVSSTNCKNVCRTEGFPTGSCDFHITSRKCYCYKPCP
-
Sequence Length
- 50
-
UniProt Entry
- A4L7R8
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- 7LNS
-
Predicted Structure
- There is no predicted structure for DRAMP00751.
Physicochemical Information
-
Formula
- C240H375N69O70S9
Absent Amino Acids
- LQW
Common Amino Acids
- C
Mass
- 5635.58
PI
- 9.18
Basic Residues
- 10
Acidic Residues
- 2
Hydrophobic Residues
- 7
Net Charge
- +8
-
Boman Index
- -102.64
Hydrophobicity
- -0.562
Aliphatic Index
- 21.4
Half Life
-
- Mammalian:1 hour
- Yeast:2 min
- E.coli:2 min
Extinction Coefficient Cystines
- 4970
Absorbance 280nm
- 101.43
Polar Residues
- 26
DRAMP00751
Comments Information
Function
- Plant defense peptide. Has antifungal activity.
PTM
- Contains three disulfide bonds (By similarity).
Literature Information
- ·Literature 1
-
Title
- Molecular cloning and characterization of Scotch pine Defensin-2.
-
Pubmed ID
- 19253756
-
Reference
- Tsitol Genet. 2008 Nov-Dec;42(6):55-60.
-
Author
- Koval'ova VA, Hut RT.