General Information

    • DRAMP ID

    • DRAMP00998

    • Peptide Name

    • Antimicrobial peptide MBP-1 (Maize Basic Peptide 1; Plant defensin)

    • Source

    • Zea mays (Maize)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • RSGRGECRRQCLRRHEGQPWETQECMRRCRRRG

    • Sequence Length

    • 33

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal

    • Target Organism

      • Gram-negative bacterium: Escherichia coli;
      • Gram-positive bacterium: Corynebacterium nebraskense ssp.
      • Fungi: Fusarium graminearum, Fusarium moniliforme, Aspergillus flavus, Alonina longipes, Sclerotinia sclerotiorum, Sclerotinia trifoliorum.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00998 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00998.

Physicochemical Information

    • Formula

    • C161H274N72O47S5

    • Absent Amino Acids

    • ADFIKNVY

    • Common Amino Acids

    • R

    • Mass

    • 4130.7

    • PI

    • 11.35

    • Basic Residues

    • 12

    • Acidic Residues

    • 4

    • Hydrophobic Residues

    • 2

    • Net Charge

    • +8

    • Boman Index

    • -200.13

    • Hydrophobicity

    • -2.033

    • Aliphatic Index

    • 11.82

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 5750

    • Absorbance 280nm

    • 179.69

    • Polar Residues

    • 10

DRAMP00998

DRAMP00998 chydropathy plot

Comments Information

    • Function

    • Inhibitor of both bacterial and fungal growth in vitro.

Literature Information

  • ·Literature 1

    • Title

    • Purification and characterization of a novel antimicrobial peptide from maize (Zea mays L.) kernels.

    • Reference

    • J. Biol. Chem. 1992; 267:18814-18820

    • Author

    • Duvick JP, Rood T, Rao AG, Marshak DR.1992