General Information

    • DRAMP ID

    • DRAMP01277

    • Peptide Name

    • Phylloseptin-s3 (Frogs, amphibians, animals)

    • Source

    • Phyllomedusa sauvagei (Sauvage's leaf frog)

    • Family

    • Not found

    • Gene

    • preproPLS-S3

    • Sequence

    • FLSLIPHIVSGVASLAIHFG

    • Sequence Length

    • 20

    • Protein Existence

    • Homology

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01277 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01277.

Physicochemical Information

    • Formula

    • C100H156N24O24

    • Absent Amino Acids

    • CDEKMNQRTWY

    • Common Amino Acids

    • ILS

    • Mass

    • 2078.48

    • PI

    • 6.92

    • Basic Residues

    • 2

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +2

    • Boman Index

    • 29.54

    • Hydrophobicity

    • 1.565

    • Aliphatic Index

    • 156

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 5

DRAMP01277

DRAMP01277 chydropathy plot

Comments Information

    • Function

    • Amphibian defense peptide. May have antimicriobial activity.

    • PTM

    • Pyrrolidone carboxylic acid at Q1.

Literature Information

  • ·Literature 1

    • Title

    • Phylloseptins from phyllomedusa sauvagei.

    • Reference

    • Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases

    • Author

    • Abbassi F, Galanth C, Piesse C, Nicolas P, Amiche M, Ladram A.