DRAMP newly added peptides with reported activities with: stability.
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285603 opens since May 20 2013.
Institute of Medical and Pharmaceutical Biotechnology, Jiangsu Industrial Technology Research Institute.
Hanmei Xu: Director of Jiangsu Province Synthetic Peptide Drug Discovery and Evaluation Engineering Research Center.
DRAMP(Data repository of antimicrobial peptides) is an open-access and manually curated database harboring diverse annotations of AMPs including sequences, structures, activities, physicochemical, patent, clinical and reference information. The clinical dataset also includes information on the clinical trial phase, therapeutic applications, company and preclinical or clinical AMP literature sources.
DRAMP currently contains 30260 entries. DRAMP V4.0 has released. The new version particularly focuses on the clinical translation of antimicrobial peptides. To this end, we added new annotations on the serum stability and protease stability of antimicrobial peptides, which are not be included in current antimicrobial peptide databases. At the same time, the new version of the database has also undergone comprehensive updates in terms of hemolysis and cytotoxicity, adding new AMPs in clinical research and newly reported AMPs.
Data in the DRAMP is made available under an CCBY 4.0 License. You are entitled to access and use the services and download or extract data. The free services are offered for the purpose of providing access to summarized data, analytics, metadata, and bulk downloads. If you need the data from the DRAMP for research, please cite the article of original author for general and clinical AMPs, or obtain the authorization for patent AMPs.
We will conduct data mining and design work based on data collected of DRAMP, as those data are valuable for guiding develment and optimization of AMP-drugs. Prediction function based on computational strategies is also expected in our database. We will set out to establish Some high-efficient classifiers.
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