Page Not Found

NEWS:

DRAMP newly added peptides with reported activities with: stability.

Commitment:

We are responsible for maintaining the website daily and updating the database regularly. The updated information will be written in the Update page. Last updated on 2024-11-14.

322365 opens since May 20 2013.

External Links

Contact: Heng Zheng, Ph.D.
zhengh18@hotmail.com

Institute of Medical and Pharmaceutical Biotechnology, Jiangsu Industrial Technology Research Institute.

Zichun Hua: Institute of Medical and Pharmaceutical Biotechnology, Jiangsu Industrial Technology Research Institute.

Hanmei Xu: Director of Jiangsu Province Synthetic Peptide Drug Discovery and Evaluation Engineering Research Center.

Welcome to DRAMP Database

DRAMP(Data repository of antimicrobial peptides) is an open-access and manually curated database harboring diverse annotations of AMPs including sequences, structures, activities, physicochemical, patent, clinical and reference information. The clinical dataset also includes information on the clinical trial phase, therapeutic applications, company and preclinical or clinical AMP literature sources.

DRAMP currently contains 30260 entries. DRAMP V4.0 has released. The new version particularly focuses on the clinical translation of antimicrobial peptides. To this end, we added new annotations on the serum stability and protease stability of antimicrobial peptides, which are not be included in current antimicrobial peptide databases. At the same time, the new version of the database has also undergone comprehensive updates in terms of hemolysis and cytotoxicity, adding new AMPs in clinical research and newly reported AMPs.

Data in the DRAMP is made available under an CCBY 4.0 License. You are entitled to access and use the services and download or extract data. The free services are offered for the purpose of providing access to summarized data, analytics, metadata, and bulk downloads. If you need the data from the DRAMP for research, please cite the article of original author for general and clinical AMPs, or obtain the authorization for patent AMPs.

We will conduct data mining and design work based on data collected of DRAMP, as those data are valuable for guiding develment and optimization of AMP-drugs. Prediction function based on computational strategies is also expected in our database. We will set out to establish Some high-efficient classifiers.

To all regular downloads, please cite our publications. If you find some errors in the website, please send an email to 970254590@qq.com.

*Citation*:

Ma T, Liu Y, Yu B, Sun X, Yao H, Hao C, Li J, Nawaz M, Jiang X, Lao X, Zheng H. DRAMP 4.0: an open-access data repository dedicated to the clinical translation of antimicrobial peptides. Nucleic Acids Research, Volume 53, Issue D1, 6 January 2025, Pages D403-D410. PMID: 39526377

New Released Structures

NEWS & EVENTS

➢Nov 14,2024 DRAMP 4.0 has been published, and welcome to read and cite it.
➢Sep 8,2024 179 Expanded amps are added to DRAMP.
➢June 20, 2024 26 stability data of antimicrobial peptides have been updated in DRAMP, e.g. DRAMP29925, DRAMP29935, and DRAMP29938.
➢May 22,2024 172 patent peptides have been updated in DRAMP.
➢Apr 11,2024 DRAMP V4.0 has released.
➢March 23,2024 Database maintenance have been performed to ensure optimal performance and data integrity.
➢Feb 28,2024 19 stability data of antimicrobial peptides have been updated in DRAMP.
➢Jan 16,2024 119 patent peptides have been updated in DRAMP.
➢Nov 4,2023 29 stapled peptides have been updated in DRAMP.
➢Aug 16,2023 37 stability data of antimicrobial peptides have been added to DRAMP.
➢July 4,2023 PDB ID of 95 entries with reported structure in PDB database have been updated.
MORE...

About Us

The database is developed by Dr.Zheng's team. This is the home page of the database, please use the navigation bar in the top of page to browse the database. If you encounter any problems in using this database, you can consult the FAQs/help pages for help or send an email 970254590@qq.com to us, we will help you solve as soon as possible.