Browse, Create and Mining Antimicrobial Peptides

Commitment:

We are responsible for maintaining the website daily and updating the database regularly. The updated information will be written in the Update page. Last updated on 2019-06-06.

87716 opens since May 20 2013.

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Contact: Zheng Heng, Ph.D.
Sub-platform of Biomedicine Technology Transfer of Technology Transfer Platform, Nanjing University National Demonstration Base for Innovation and Entrepreneurship;
School of Life Science and Technology, China Pharmaceutical University;
Institute of Medical and Pharmaceutical Biotechnology, Jiangsu Industrial Technology Research Institute
zhengh18@hotmail.com

Welcome to DRAMP Database

DRAMP(Data repository of antimicrobial peptides) is an open-access and manually curated database harboring diverse annotations of AMPs including sequences, structures, activities, physicochemical, patent, clinical and reference information. The clinical dataset also includes information on the clinical trial phase, therapeutic applications, company and preclinical or clinical AMP literature sources.

DRAMP currently contains 19899 entries, 5084 of which are general AMPs (containing natural and synthetic AMPs), 14739 patent AMPs and 76 AMPs in drug development (preclinical or clinical stage).

Data in the DRAMP is made available under an CCBY 4.0 License. You are entitled to access and use the services and download or extract data. The free services are offered for the purpose of providing access to summarised data, analytics or metadata, and are distinguished from bulk downloads or data-feeds. If you need the data from the DRAMP for research, please cite the article of original author for general and clinical AMPs, or obtain the authorization for patented AMPs.

We will conduct data mining and design work based on data collected of DRAMP, as those data are valuable to guide AMP-drug development and optimization. Prediction function based on computational strategies is also expected in our database. We will set out to establish Some high-efficient classifiers.

To all regular downloads, please cite our publications.

Read more

Citing Us:

  • Liu S.; Bao J.; Lao X.; Zheng H. Novel 3D Structure Based Model for Activity Prediction and Design of Antimicrobial Peptides. Sci Rep. 2018 Jul 25;8(1):11189. PMID:30046138
  • Liu S.; Fan L.; Sun J.; Lao X.; Zheng H. Computational resources and tools for antimicrobial peptides. J Pept Sci. 2017 Jan;23(1):4-12. PMID:27966278
  • Fan, L.; Sun, J.; Zhou, M.; Zhou, J.; Lao, X.; Zheng, H.; Xu, H. DRAMP: a comprehensive data repository of antimicrobial peptides. Sci Rep. 2016 Apr 14;6:24482. PMID: 27075512
  • New Released Structures

    NEWS & EVENTS

    • June 6,2019 59 entries are re-updated in the General dataset. The page of Quicklink is updated.
    • April 3,2019 632 entries are re-updated in the General dataset. Some errors are fixed.
    • January 1,2019 2041 new entries are added in DRAMP. 4 entries are bacteriocins in natural dataset, 2035 entries are patent AMPs, 2 entries in clinicaltrials.
    • October 30,2018 DRAMP V2.0 has released! Please click on More below to view the details of this update.
    • September 28,2018 DRAMP V2.0 will be released in October! Welcome to comments and suggestions!
    • September 27,2018 91 DRAMP entries are re-updated in the General dataset. 90 entries are natural AMPs including 1 bacteriocin and 3 plant AMPs, 1 entry is synthetic AMP.
    • July 12,2018 12 error entries of AMPs are fixed in the General dataset. 11 repeated entries are deleted.
    • MORE...

    About Us

    The database is developed by Dr.Zheng's team. This is the home page of the database, please use the navigation bar in the top of page to browse the database. If you encounter any problems in using this database, you can consult the FAQs/help pages for help or feedback to us, we will help you solve as soon as possible.

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