Browse, Create and Mining Antimicrobial Peptides

Commitment:

we are responsible for maintaining the website daily and updating the database regularly. The updated information will be written in the Update page. Last updated on 2018-10-30.

80605 opens since May 20 2013.

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Contact: Zheng Heng, Ph.D.
Sub-platform of Biomedicine Technology Transfer of Technology Transfer Platform, Nanjing University National Demonstration Base for Innovation and Entrepreneurship;
School of Life Science and Technology, China Pharmaceutical University;
Institute of Medical and Pharmaceutical Biotechnology, Jiangsu Industrial Technology Research Institute
zhengh18@hotmail.com

Welcome to DRAMP Database

DRAMP (data repository of antimicrobial peptides) was launched online on May 20, 2013. DRAMP is an open-access and manually curated database harboring diverse annotations of AMPs including sequence information, structure information, antimicrobial activity information, hemolytic activity information, physicochemical information, patent information, clinical information and reference information. DRAMP currently contains 17858 entries, including 5080 general AMPs, 12704 patents and 74 peptides in drug development.

Clinical dataset is specically incorporated in our database, providing information of sequence, structure, activity (MIC in vitro), clinical trail, therapeutic application, company and a summary of literature sources of pre- or clinical AMPs, in order to offer a data source for drug development of antimicrobials.

Next, we will conduct data mining work and design work based on our collection of AMPs, as those data are valuable to guide AMP-drug development and optimization.

Prediction function based on computational strategies is also expected in our database. We set out to establish a high-efficient classifier on the large general dataset and consider to analyse the clinical dataset, though relatively small, using bioinformatic methods.

Read more

Citing Us:

  • Liu S.; Bao J.; Lao X.; Zheng H. Novel 3D Structure Based Model for Activity Prediction and Design of Antimicrobial Peptides. Sci Rep. 2018 Jul 25;8(1):11189. PMID:30046138
  • Liu S.; Fan L.; Sun J.; Lao X.; Zheng H. Computational resources and tools for antimicrobial peptides. J Pept Sci. 2017 Jan;23(1):4-12. PMID:27966278
  • Fan, L.; Sun, J.; Zhou, M.; Zhou, J.; Lao, X.; Zheng, H.; Xu, H. DRAMP: a comprehensive data repository of antimicrobial peptides. Sci Rep. 2016 Apr 14;6:24482. PMID: 27075512
  • New Released Structures

    NEWS & EVENTS

    • October 30,2018 DRAMP V2.0 has released! Please click on More below to view the details of this update.
    • September 28,2018 DRAMP V2.0 will be released in October! Welcome to comments and suggestions!
    • September 27,2018 91 DRAMP entries are re-updated in the General dataset. 90 entries are nature AMPs including 1 bacteriocin and 3 plant AMPs, 1 entry is synthetic AMP.
    • July 12,2018 12 error entries of AMPs are fixed in the General dataset. 11 repeated entries are deleted.
    • June 6,2018 8 new natural entries of AMPs are added to the General dataset. 3 error entries of AMPs are fixed in the General dataset. 4 useless entries are deleted. Citing US and some pages are updated. Some errors are fixed.
    • March 2,2018 28 new entries of AMPs are added to the General dataset, including 11 natural AMPs and 17 synthetic AMPs. Some errors are fixed.
    • MORE...

    About Us

    The database is developed by Dr.Zheng's team. This is the home page of the database, please use the navigation bar in the top of page to browse the database. If you encounter any problems in using this database, you can consult the FAQs/help pages for help or feedback to us, we will help you solve as soon as possible.

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