General Information

    • DRAMP ID

    • DRAMP01289

    • Peptide Name

    • Phylloseptin-1 (PStar 01; Frogs, amphibians, animals)

    • Source

    • Phyllomedusa tarsius (Brownbelly leaf frog) (Phyllomedusa tarsia)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FLSLIPKIAGGIASLVKNL

    • Sequence Length

    • 19

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01289 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01289.

Physicochemical Information

    • Formula

    • C93H160N22O23

    • Absent Amino Acids

    • CDEHMQRTWY

    • Common Amino Acids

    • L

    • Mass

    • 1954.43

    • PI

    • 10

    • Basic Residues

    • 2

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +2

    • Boman Index

    • 22.42

    • Hydrophobicity

    • 1.263

    • Aliphatic Index

    • 169.47

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 5

DRAMP01289

DRAMP01289 chydropathy plot

Comments Information

    • Function

    • Has antimicrobial activity.

    • Tissue specificity

    • Expressed by the skin glands.

    • PTM

    • C-terminal amidation.

Literature Information

  • ·Literature 1

    • Title

    • Dermaseptins and phylloseptins from Phyllomedusa tarsius (Amphibia).

    • Reference

    • Submitted (AUG-2006) to UniProtKB

    • Author

    • Prates M.V, Jardim D.P, Silva L.P, Gordo M, Leite J.R.S.A, Figueredo R.C.R, Amaral A.C, Felipe M.S.S, Bloch C. Jr.