General Information
-
DRAMP ID
- DRAMP01294
-
Peptide Name
- Tryptophyllin-5.1 (Frogs, amphibians, animals)
-
Source
- Phyllomedusa hypochondrialis (Orange-legged leaf frog)
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Family
- Belongs to the frog skin active peptide family (Tryptophillin subfamily)
-
Gene
- Not found
-
Sequence
- FPPWL
-
Sequence Length
- 5
-
UniProt Entry
- P84573
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01294.
Physicochemical Information
-
Formula
- C36H46N6O6
Absent Amino Acids
- ACDEGHIKMNQRSTVY
Common Amino Acids
- P
Mass
- 658.8
PI
- 5.52
Basic Residues
- 0
Acidic Residues
- 0
Hydrophobic Residues
- 3
Net Charge
- 0
-
Boman Index
- 10.23
Hydrophobicity
- 0.5
Aliphatic Index
- 78
Half Life
-
- Mammalian:1.1 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 5500
Absorbance 280nm
- 1375
Polar Residues
- 0
DRAMP01294
Comments Information
Function
- Amphibian defense peptide. May have antimicriobial activity.
Tissue specificity
- Expressed by the skin glands.
Literature Information
- ·Literature 1
-
Title
- High-throughput imaging co-localization of peptides and proteins.
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Pubmed ID
- PubMed ID is not available
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Reference
- Nat. Chem. Biol. 0:0-0(2007)
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Author
- Silva LP, Brand GD, Bloch C Jr.
