• • DRAMP ID

  • DRAMP01358

• • Peptide Name

  • Ranalexin-Vb (Frogs, amphibians, animals)

• • Source

  • Rana virgatipes (Ranidae) (Aquarana)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • FLGGLFKLVPSVICAVTKKC

• • Sequence Length

  • 20

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Protein level

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-negative bacterium: Escherichia coli (MIC=12 µM);
    • Gram-positive bacterium: Staphylococcus aureus (MIC=12 µM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Cyclic

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Cyclization (Cys14 and Cys20)

• • Nonterminal Modifications and Unusual Amino Acids

  • Disulfide bond between Cys14 and Cys20.

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP01358_predicted_structure.pdb to download.

DRAMP01358

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Purification and characterization of antimicrobial peptides from the skin secretions of the carpenter frog Rana virgatipes (Ranidae, Aquarana).

• • Pubmed ID

  • 15996769

• • Reference

  • Regul Pept 2005; 131: 38-45.

• • Author

  • Conlon JM et al Bevier CR.