• • DRAMP ID

  • DRAMP01394

• • Peptide Name

  • Odorranain-W2 (Frogs, amphibians, animals)

• • Source

  • Odorrana grahami (Yunnanfu frog)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • GLLRASSVWGRKYYVDLAGCAKA

• • Sequence Length

  • 23

• • UniProt Entry

  • A7YL71

• • Protein Existence

  • Homology

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal

• • Target Organism

  • • Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=30 µg/ml), Bacillus dysenteriae (MIC=30 µg/ml), Helicobacter pylori NCTC 11637 (MIC=20 µg/ml);
    • Gram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=5 µg/ml).
    • Yeast: Candida albicans ATCC 2002 (MIC=25 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

  • Free

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP01394_predicted_structure.pdb to download.

DRAMP01394

• • Function

  • Shows antibacterial and antifungal activities.

• ·Literature 1

• • Title

  • An antimicrobial peptide with antimicrobial activity against Helicobacter pylori.

• • Pubmed ID

  • 17698252

• • Reference

  • Peptides. 2007 Aug;28(8):1527-1531.

• • Author

  • Chen L, Li Y, Li J, Xu X, Lai R, Zou Q.