• • DRAMP ID

  • DRAMP01423

• • Peptide Name

  • Nigrosin-OG13 (Frogs, amphibians, animals)

• • Source

  • Odorrana grahami (Yunnanfu frog)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • GLLSGILGAGKHIVCGLSGLR

• • Sequence Length

  • 21

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal

• • Target Organism

  • • Gram-negative bacterium: Escherichia coli (MIC=4.68 µg/ml);
    • Gram-positive bacteria: Staphylococcus aureus (MIC=9.37 µg/ml), Bacillus subtilis (MIC=18.75 µg/ml).
    • Yeast: Candida albicans (MIC=1.10 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

  • Free

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP01423_predicted_structure.pdb to download.

DRAMP01423

• • Function

  • Has antibacterial and antifungal activity.

• ·Literature 1

• • Title

  • Anti-infection peptidomics of amphibian skin.

• • Pubmed ID

  • 17272268

• • Reference

  • Mol Cell Proteomics. 2007 May;6(5):882-894.

• • Author

  • Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J.