General Information

    • DRAMP ID

    • DRAMP01536

    • Peptide Name

    • Nigroain-B4 (Frogs, amphibians, animals)

    • Source

    • Rana nigrovittata (Black-striped frog)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • CVISAGWNHKIR

    • Sequence Length

    • 12

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Bridge

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01536 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01536.

Physicochemical Information

    • Formula

    • C61H98N20O15S

    • Absent Amino Acids

    • DEFLMPQTY

    • Common Amino Acids

    • I

    • Mass

    • 1383.63

    • PI

    • 9.51

    • Basic Residues

    • 3

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +3

    • Boman Index

    • -14.93

    • Hydrophobicity

    • 0.025

    • Aliphatic Index

    • 97.5

    • Half Life

      • Mammalian:1.2 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 500

    • Polar Residues

    • 4

DRAMP01536

Comments Information

    • PTM

    • Contains one disulfide bridge.

Literature Information

  • ·Literature 1

    • Title

    • Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovitt.

    • Reference

    • Genomics. 2010 Jan;95(1):66-71.

    • Author

    • Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R.