General Information
-
DRAMP ID
- DRAMP01632
-
Peptide Name
- Dermaseptin-S8 (Frogs, amphibians, animals)
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Source
- Phyllomedusa sauvagei (Sauvage's leaf frog)
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Family
- Not found
-
Gene
- Not found
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Sequence
- ALWKTMLKKLGTVALHAGKAALGAAADTISQ
-
Sequence Length
- 31
-
UniProt Entry
- No entry found
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Protein Existence
- Predicted
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Antifungal, Antiviral
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Alpha helix
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP01632.
Physicochemical Information
-
Formula
- C141H239N39O39S
Absent Amino Acids
- CEFNPRY
Common Amino Acids
- A
Mass
- 3136.75
PI
- 10
Basic Residues
- 5
Acidic Residues
- 1
Hydrophobic Residues
- 16
Net Charge
- +4
-
Boman Index
- 3.31
Hydrophobicity
- 0.426
Aliphatic Index
- 110.65
Half Life
-
- Mammalian:4.4 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 5500
Absorbance 280nm
- 183.33
Polar Residues
- 7
DRAMP01632
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Identification of three novel Phyllomedusa sauvagei dermaseptins (sVI-sVIII) by cloning from a skin secretion-derived cDNA library.
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Pubmed ID
- 14599725
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Reference
- Regul Pept. 2003 Nov 15;116(1-3):139-146.
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Author
- Chen T, Tang L, Shaw C.