• DRAMP ID

    • DRAMP01985
    • Peptide Name

    • Brevinin-2HS1 (Frogs, amphibians, animals)
    • Source

    • Huia schmackeri (Chinese piebald odorous frog)
    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)
    • Gene

    • Not found
    • Sequence

    • GLWDTIKQAGKKIFLSVLDKIRCKVAGGC
    • Sequence Length

    • 29
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal, Antiviral
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01985 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01985.
    • Formula

    • C142H239N39O37S2
    • Absent Amino Acids

    • EHMNPY
    • Common Amino Acids

    • K
    • Mass

    • 3148.82
    • PI

    • 9.59
    • Basic Residues

    • 6
    • Acidic Residues

    • 2
    • Hydrophobic Residues

    • 12
    • Net Charge

    • +4
    • Boman Index

    • -18.77
    • Hydrophobicity

    • 0.214
    • Aliphatic Index

    • 107.59
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 5625
    • Absorbance 280nm

    • 200.89
    • Polar Residues

    • 8

DRAMP01985

DRAMP01985 chydropathy plot
    • Function

    • Antimicrobial peptide homologs.
    • Tissue specificity

    • Expressed by the skin glands.
  • ·Literature 1
    • Title

    • Novel brevinins from Chinese piebald odorous frog (Huia schmackeri) skin deduced from cloned biosynthetic precursors.
    • Reference

    • Peptides. 2008 Aug;29(8):1456-1460.
    • Author

    • Quan Z, Zhou M, Chen W, Chen T, Walker B, Shaw C.