General Information
-
DRAMP ID
- DRAMP01985
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Peptide Name
- Brevinin-2HS1 (Frogs, amphibians, animals)
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Source
- Huia schmackeri (Chinese piebald odorous frog)
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Family
- Belongs to the frog skin active peptide family (Brevinin subfamily)
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Gene
- Not found
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Sequence
- GLWDTIKQAGKKIFLSVLDKIRCKVAGGC
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Sequence Length
- 29
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UniProt Entry
- No entry found
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Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Antifungal, Antiviral
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP01985.
Physicochemical Information
-
Formula
- C142H239N39O37S2
Absent Amino Acids
- EHMNPY
Common Amino Acids
- K
Mass
- 3148.82
PI
- 9.59
Basic Residues
- 6
Acidic Residues
- 2
Hydrophobic Residues
- 12
Net Charge
- +4
-
Boman Index
- -18.77
Hydrophobicity
- 0.214
Aliphatic Index
- 107.59
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 5625
Absorbance 280nm
- 200.89
Polar Residues
- 8
DRAMP01985
Comments Information
Function
- Antimicrobial peptide homologs.
Tissue specificity
- Expressed by the skin glands.
Literature Information
- ·Literature 1
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Title
- Novel brevinins from Chinese piebald odorous frog (Huia schmackeri) skin deduced from cloned biosynthetic precursors.
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Pubmed ID
- 18423796
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Reference
- Peptides. 2008 Aug;29(8):1456-1460.
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Author
- Quan Z, Zhou M, Chen W, Chen T, Walker B, Shaw C.