General Information
-
DRAMP ID
- DRAMP02006
-
Peptide Name
- Brevinin-2Va (Frogs, amphibians, animals)
-
Source
- Rana virgatipes (Ranidae) (Aquarana)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- GIWDTLKNVGKAVLGKVLENV
-
Sequence Length
- 21
-
UniProt Entry
- No entry found
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram-
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Target Organism
-
- Gram-negative bacterium: Escherichia coli (MIC=12 µM).
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP02006.
Physicochemical Information
-
Formula
- C103H173N27O29
Absent Amino Acids
- CFHMPQRSY
Common Amino Acids
- V
Mass
- 2253.67
PI
- 8.5
Basic Residues
- 3
Acidic Residues
- 2
Hydrophobic Residues
- 10
Net Charge
- +1
-
Boman Index
- -5.23
Hydrophobicity
- 0.286
Aliphatic Index
- 134.29
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 5500
Absorbance 280nm
- 275
Polar Residues
- 6
DRAMP02006
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- Purification and characterization of antimicrobial peptides from the skin secretions of the carpenter frog Rana virgatipes (Ranidae, Aquarana).
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Pubmed ID
- 15996769
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Reference
- Regul Pept. 2005 Nov;131(1-3):38-45.
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Author
- Conlon JM, Abraham B, Sonnevend A, Jouenne T, Cosette P, Leprince J, Vaudry H, Bevier CR.