General Information

    • DRAMP ID

    • DRAMP02783

    • Peptide Name

    • Peptide C (Insects, animals)

    • Source

    • Zophobas atratus (Giant mealworm beetle)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FTCDVLGFEIAGTKLNSAACGAHCLALGRTGGYCNSKSVCVCR

    • Sequence Length

    • 43

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

    • Target Organism

      • Gram-negative bacterium: Escherichia coli D22;
      • Gram-positive bacteria: Micrococcus luteus, Corynebacterium D2, Streptococcus pyogenes, Bacillus subtilis QB935.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02783 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02783.

Physicochemical Information

    • Formula

    • C185H299N55O57S6

    • Absent Amino Acids

    • MPQW

    • Common Amino Acids

    • CG

    • Mass

    • 4398.1

    • PI

    • 8.34

    • Basic Residues

    • 5

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 15

    • Net Charge

    • +3

    • Boman Index

    • -27.41

    • Hydrophobicity

    • 0.458

    • Aliphatic Index

    • 77.21

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 1865

    • Absorbance 280nm

    • 44.4

    • Polar Residues

    • 21

DRAMP02783

DRAMP02783 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Insect immunity. Isolation from a coleopteran insect of a novel inducible antibacterial peptide and of new members of the insect defensin family.

    • Reference

    • J Biol Chem. 1991 Dec 25;266(36):24520-24525.

    • Author

    • Bulet P, Cociancich S, Dimarcq JL, Lambert J, Reichhart JM, Hoffmann D, Hetru C, Hoffmann JA.