General Information

    • DRAMP ID

    • DRAMP02791

    • Peptide Name

    • A.dichotoma defensin (defensins; Insects, animals)

    • Source

    • Allomyrina dichotoma (Japanese rhinoceros beetle)

    • Family

    • Belongs to the invertebrate defensin family (Type 1 subfamily)

    • Gene

    • Not found

    • Sequence

    • VTCDLLSFEAKGFAANHSLCAAHCLAIGRRGGSCERGVCICRR

    • Sequence Length

    • 43

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+

    • Target Organism

      • Gram-positive bacteria: Staphylococcus aureus, Bacillus subtilis, Staphylococcus aureus (MRSA).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Bridge

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02791 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02791.

Physicochemical Information

    • Formula

    • C189H312N64O55S6

    • Absent Amino Acids

    • MPQWY

    • Common Amino Acids

    • AC

    • Mass

    • 4553.31

    • PI

    • 8.7

    • Basic Residues

    • 8

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 16

    • Net Charge

    • +5

    • Boman Index

    • -64.42

    • Hydrophobicity

    • 0.281

    • Aliphatic Index

    • 81.86

    • Half Life

      • Mammalian:100 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 375

    • Absorbance 280nm

    • 8.93

    • Polar Residues

    • 16

DRAMP02791

DRAMP02791 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Isolation and characterization of a new member of the insect defensin family from a beetle, Allomyrina dichotoma.

    • Reference

    • Biochem Biophys Res Commun. 1996 Mar 27;220(3):526-531.

    • Author

    • Miyanoshita A, Hara S, Sugiyama M, Asaoka A, Taniai K, Yukuhiro F, Yamakawa M.