General Information

    • DRAMP ID

    • DRAMP02812

    • Peptide Name

    • Endopeptidase L4

    • Source

    • Lysobacter sp. strain XL1 (Gram-negative bacteria)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • AVVNGVNYVGETTAA

    • Sequence Length

    • 15

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02812 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02812.

Physicochemical Information

    • Formula

    • C63H101N17O23

    • Absent Amino Acids

    • CDFHIKLMPQRSW

    • Common Amino Acids

    • V

    • Mass

    • 1464.6

    • PI

    • 4

    • Basic Residues

    • 0

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 7

    • Net Charge

    • -1

    • Boman Index

    • -1.9

    • Hydrophobicity

    • 0.547

    • Aliphatic Index

    • 97.33

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 106.43

    • Polar Residues

    • 7

DRAMP02812

Comments Information

    • Biophysicochemical properties

    • Optimum pH is 8.0; Optimum temperature is 50-55 degrees Celsius. Retains 50% of its maximal activity after incubation at 52 degrees Celsius for 15 min.

Literature Information

  • ·Literature 1

    • Title

    • Isolation and characterization of a new extracellular bacteriolytic endopeptidase of Lysobacter sp. XL1.

    • Reference

    • Biochemistry (Mosc). 2005 Sep;70(9):1031.

    • Author

    • Stepnaya OA, Tsfasman IM, Logvina IA, Ryazanova LP, Muranova TA, Kulaev IS.