• DRAMP ID

    • DRAMP02816
    • Peptide Name

    • Lumbrican
    • Source

    • Lumbricus rubellus (humus earthworm)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • RQKDKRPYSERKNQYTGPQFLYPPERIPP
    • Sequence Length

    • 29
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
    • Target Organism

      • Gram-positive bacteria: Bacillus subtilis ATCC 62037, Staphylococcus aureus ATCC 15752, Streptococcus mutans ATCC 25175;
      • Gram-negative bacteria: Escherichia coli ATCC 27325, Pseudomonas putida ATCC 17426, Serratia sp. ATCC 21074.
      • Fungi: Candida albicans ATCC 10231, Cryptococcus neoformans ATCC 34881, Saccharomyces cerevisiae ATCC 44774.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02816 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02816.
    • Formula

    • C162H250N48O45
    • Absent Amino Acids

    • ACHMVW
    • Common Amino Acids

    • P
    • Mass

    • 3590.06
    • PI

    • 9.99
    • Basic Residues

    • 7
    • Acidic Residues

    • 3
    • Hydrophobic Residues

    • 3
    • Net Charge

    • +4
    • Boman Index

    • -114.56
    • Hydrophobicity

    • -2.017
    • Aliphatic Index

    • 26.9
    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 4470
    • Absorbance 280nm

    • 159.64
    • Polar Residues

    • 7

DRAMP02816

DRAMP02816 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Lumbricin I, a novel proline-rich antimicrobial peptide from the earthworm: purification, cDNA cloning and molecular characterization.
    • Reference

    • Biochim Biophys Acta. 1998 Oct 22;1408(1):67-76.
    • Author

    • Cho JH, Park CB, Yoon YG, Kim SC.