General Information

    • DRAMP ID

    • DRAMP02836

    • Peptide Name

    • Cathelicidin antimicrobial peptide (cathelicidin; mammals, animals)

    • Source

    • Bos taurus (Bovine)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • QCVGTITLDQSDDLFDLNCNELQSVR

    • Sequence Length

    • 26

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02836 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02836.

Physicochemical Information

    • Formula

    • C121H196N34O46S2

    • Absent Amino Acids

    • AHKMPWY

    • Common Amino Acids

    • DL

    • Mass

    • 2927.21

    • PI

    • 3.71

    • Basic Residues

    • 1

    • Acidic Residues

    • 5

    • Hydrophobic Residues

    • 8

    • Net Charge

    • -4

    • Boman Index

    • -59.29

    • Hydrophobicity

    • -0.269

    • Aliphatic Index

    • 97.31

    • Half Life

      • Mammalian:0.8 hour
      • Yeast:10 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 5

    • Polar Residues

    • 9

DRAMP02836

DRAMP02836 chydropathy plot

Comments Information

    • One chain of Cathelicidin antimicrobial peptide.

Literature Information

  • ·Literature 1

    • Title

    • Purification and structural characterization of bovine cathelicidins, precursors of antimicrobial peptides.

    • Reference

    • Eur J Biochem. 1996 Jun 15;238(3):769-776.

    • Author

    • Storici P, Tossi A, Lenarcic B, Romeo D.