General Information

    • DRAMP ID

    • DRAMP04655

    • Peptide Name

    • Hymenochirin-2B

    • Source

    • Hymenochirus boettgeri

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • LKIPGFVKDTLKKVAKGIFSAVAGAMTPS

    • Sequence Length

    • 29

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04655 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

Physicochemical Information

    • Formula

    • C138H232N34O36S

    • Absent Amino Acids

    • CEHNQRWY

    • Common Amino Acids

    • K

    • Mass

    • 2975.63

    • PI

    • 10.18

    • Basic Residues

    • 5

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 13

    • Net Charge

    • +4

    • Boman Index

    • 1.76

    • Hydrophobicity

    • 0.466

    • Aliphatic Index

    • 97.59

    • Half Life

      • Mammalian:5.5 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 7

DRAMP04655

DRAMP04655 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • The hymenochirins: A family of host-defense peptides from the Congo dwarf clawed frog Hymenochirus boettgeri (Pipidae).

    • Reference

    • Peptides. 2012 Jun;35(2):269-275.

    • Author

    • Mechkarska M, Prajeep M, Coquet L, Leprince J, Jouenne T, Vaudry H, King JD, Conlon JM.