• DRAMP ID

    • DRAMP00020
    • Peptide Name

    • HalA1 (one chain of haloduracin; Bacteriocin)
    • Source

    • Bacillus halodurans C-125 (Gram-positive bacteria)
    • Family

    • Belongs to the lantibiotic family (Class I bacteriocin)
    • Gene

    • Unknow
    • Sequence

    • CAWYNISCRLGNKGAYCTLTVECMPSCN
    • Sequence Length

    • 28
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknow
    • Biological Activity

    • Antibacterial
    • Target Organism

      • No MICs found on DRAMP database
    • Binding Traget

    • Surface of a bacterial target
    • Structure

    • Rich
    • Structure Description

    • Unknow
    • PDB ID

    • Unknow
    • DRAMP00020 helical wheel diagram
    • Formula

    • C130H202N36O40S6
    • Absent Amino Acids

    • DFHQ
    • Common Amino Acids

    • C
    • Mass

    • 3583.4
    • PI

    • 7.81
    • Basic Residues

    • 2
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 7
    • Boman Index

    • -24.04
    • Hydrophobicity

    • 10.71
    • Aliphatic Index

    • 59.29
    • Half Life

      • Mammalian:1.2 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 8730
    • Absorbance 280nm

    • 323.33
    • Polar Residues

    • 16
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Amino Acid Distribution

DRAMP00020 chydropathy plot
    • Function

    • Active on certain Gram-positive bacteria.
  • Literature 1
    • Reference

    • Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17243-17248.
    • Author

    • McClerren AL, Cooper LE, Quan C, Thomas PM, Kelleher NL, van der Donk WA.
    • Title

    • Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic.