• DRAMP ID

    • DRAMP00020
    • Peptide Name

    • HalA1 (one chain of haloduracin; Bacteriocin)
    • Source

    • Bacillus halodurans C-125 (Gram-positive bacteria)
    • Family

    • Belongs to the lantibiotic family (Class I bacteriocin)
    • Gene

    • Not found
    • Sequence

    • CAWYNISCRLGNKGAYCTLTVECMPSCN
    • Sequence Length

    • 28
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Surface of a bacterial target
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Rich
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP00020 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP00020.
    • Formula

    • C130H202N36O40S6
    • Absent Amino Acids

    • DFHQ
    • Common Amino Acids

    • C
    • Mass

    • 3101.61
    • PI

    • 7.82
    • Basic Residues

    • 2
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 7
    • Net Charge

    • +1
    • Boman Index

    • -24.04
    • Hydrophobicity

    • 0.107
    • Aliphatic Index

    • 59.29
    • Half Life

      • Mammalian:1.2 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 8730
    • Absorbance 280nm

    • 323.33
    • Polar Residues

    • 16

DRAMP00020

DRAMP00020 chydropathy plot
    • Function

    • Active on certain Gram-positive bacteria.
  • ·Literature 1
    • Title

    • Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic.
    • Reference

    • Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17243-17248.
    • Author

    • McClerren AL, Cooper LE, Quan C, Thomas PM, Kelleher NL, van der Donk WA.