• DRAMP ID

    • DRAMP00051
    • Peptide Name

    • Mutacin I (Bacteriocin)
    • Source

    • Streptococcus mutans CH43); also Streptococcus mutans UA140 (Gram-positive bacteria)
    • Family

    • Belongs to the type A lantibiotic family (Class I bacteriocin)
    • Gene

    • Unknown
    • Sequence

    • FSSLSLCSLGCTGVKNPSFNSYCC
    • Sequence Length

    • 24
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknown
    • Biological Activity

    • Antibacterial, Anti-Gram+, Antimicrobial
    • Target Organism

      • Gram-positive bacteria: Staphylococcus aureus, Staphylococcus epidermidis, enterococci, pneumococci, group A streptococci.
    • Hemolytic activity

    • Unknown
    • Binding Target

    • Unknown
    • Structure

    • Unknown
    • Structure Description

    • Unknown
    • DRAMP00051 helical wheel diagram
    • Formula

    • C107H165N27O35S4
    • Absent Amino Acids

    • ADEHIMQRW
    • Common Amino Acids

    • S
    • Mass

    • 2928.3
    • PI

    • 7.91
    • Basic Residues

    • 1
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 6
    • Boman Index

    • -10.18
    • Hydrophobicity

    • 46.25
    • Aliphatic Index

    • 60.83
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 1740
    • Absorbance 280nm

    • 75.65
    • Polar Residues

    • 16

DRAMP00051

DRAMP00051 chydropathy plot
    • No comments found on DRAMP database

  • Literature 1
    • Reference

    • Appl Environ Microbiol. 2000 Aug;66(8):3221-3229.
    • Author

    • Qi F, Chen P, Caufield PW.
    • Title

    • Purification and biochemical characterization of mutacin I from the group I strain of Streptococcus mutans, CH43, and genetic analysis of mutacin I biosynthesis genes.
  • Literature 2
    • Reference

    • Appl Environ Microbiol. 2001 Jan;67(1):15-21.
    • Author

    • Qi F, Chen P, Caufield PW.
    • Title

    • The group I strain of Streptococcus mutans, UA140, produces both the lantibiotic mutacin I and a nonlantibiotic bacteriocin, mutacin IV.