• DRAMP ID

    • DRAMP00054
    • Peptide Name

    • Nisin Q (Bacteriocin)
    • Source

    • Lactococcus lactis 61-14 (Gram-positive bacteria)
    • Family

    • Belongs to the type A lantibiotic family (Class I bacteriocin)
    • Gene

    • nisQ
    • Sequence

    • ITSISLCTPGCKTGVLMGCNLKTATCNCSVHVSK
    • Sequence Length

    • 34
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknown
    • Biological Activity

    • Antibacterial, Anti-Gram+, Antimicrobial
    • Target Organism

      • Gram-positive bacteria: LAB, Bacillus sp, Listeria sp, Micrococcus sp.
    • Hemolytic activity

    • Unknown
    • Binding Target

    • Unknown
    • Structure

    • Unknown
    • Structure Description

    • Unknown
    • DRAMP00054 helical wheel diagram
    • Formula

    • C143H249N41O46S6
    • Absent Amino Acids

    • DEFQRWY
    • Common Amino Acids

    • CT
    • Mass

    • 4059.97
    • PI

    • 8.51
    • Basic Residues

    • 4
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 9
    • Boman Index

    • -10.94
    • Hydrophobicity

    • 52.35
    • Aliphatic Index

    • 85.88
    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 250
    • Absorbance 280nm

    • 7.58
    • Polar Residues

    • 19

DRAMP00054

DRAMP00054 chydropathy plot
    • Function

    • defense response to Gram-positive bacteria.
  • Literature 1
    • Reference

    • Biosci Biotechnol Biochem. 2003 Jul;67(7):1616-1619.
    • Author

    • Zendo T, Fukao M, Ueda K, Higuchi T, Nakayama J, Sonomoto K.
    • Title

    • Identification of the lantibiotic nisin Q, a new natural nisin variant produced by Lactococcus lactis 61-14 isolated from a river in Japan.