General Information

    • DRAMP ID

    • DRAMP00069

    • Peptide Name

    • Garvieacin Q (GarQ; Bacteriocin)

    • Source

    • Lactococcus garvieae BCC 43578 (Gram-positive bacteria)

    • Family

    • Belongs to the class II bacteriocin

    • Gene

    • Unknow

    • Sequence

    • EYHLMNGANGYLTRVNGKTVYRVTKDPVSAVFGVISNCWGSAGAGFGPQH

    • Sequence Length

    • 50

    • Swiss_Prot Entry

    • No entry found

    • Evidence code

    • Unknow

Activity Information

    • Biological Activity

    • Antibacterial

    • Target Organism

      • Gram-positive bacteria: Bacillus coagulans JCM 2257, Listeria monocytogenes ATCC 19115, L. garvieae strains, E. faecium D48S52, Lactobacillus plantarum BCC 9546, Lactobacillus sakeii JCM 1157, L. ivanovii DMST 9012 (MIC=0.1-1.6 uM).

    • Hemolytic activity

    • Unknown

    • Binding Traget

    • Unknow

Structure Information

    • Structure

    • Unknow

    • Structure Description

    • Unknow

    • PDB ID

    • Unknow
    • DRAMP00069 helical wheel diagram

Physical Information

    • Formula

    • C237H358N68O69S2

    • Absent Amino Acids

    • ?

    • Common Amino Acids

    • G

    • Mass

    • 6202.17

    • PI

    • 9.19

    • Basic Residues

    • 6

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 16

    • Boman Index

    • -50.54

    • Hydrophobicity

    • -17.8

    • Aliphatic Index

    • 66.2

    • Half Life

      • Mammalian:1 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 9970

    • Absorbance 280nm

    • 203.47

    • Polar Residues

    • 22

Amino Acid Distribution

DRAMP00069 chydropathy plot

Comments Information

    • No comments found on DRAMP database

Literature Information

  • Literature 1

    • Reference

    • Appl Environ Microbiol. 2012 Mar;78(5):1619-1623.

    • Author

    • Tosukhowong A, Zendo T, Visessanguan W, Roytrakul S, Pumpuang L, Jaresitthikunchai J, Sonomoto K.

    • Title

    • Garvieacin Q, a novel class II bacteriocin from Lactococcus garvieae BCC 43578.