General Information

    • DRAMP ID

    • DRAMP00156

    • Peptide Name

    • BrcB (NKR-5-3A; chain b of Brochocin C; Bacteriocin)

    • Source

    • Brochothrix campestris ATCC 43754 (Gram-positive bacteria)

    • Family

    • Belongs to the class IIb bacteriocin

    • Gene

    • Not found

    • Sequence

    • KINWGNVGGSCVGGAVIGGALGGLGGAGGGCITGAIGSIWDQW

    • Sequence Length

    • 43

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00156 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00156.

Physicochemical Information

    • Formula

    • C173H268N50O52S2

    • Absent Amino Acids

    • EFHMPRY

    • Common Amino Acids

    • G

    • Mass

    • 3944.45

    • PI

    • 5.82

    • Basic Residues

    • 1

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 17

    • Net Charge

    • 0

    • Boman Index

    • 35.93

    • Hydrophobicity

    • 0.595

    • Aliphatic Index

    • 93.02

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 16625

    • Absorbance 280nm

    • 395.83

    • Polar Residues

    • 23

DRAMP00156

DRAMP00156 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Genetic characterization and heterologous expression of brochocin-C, an antibotulinal, two-peptide bacteriocin produced by Brochothrix campestris ATCC 43754.

    • Reference

    • Appl Environ Microbiol. 1998 Dec;64(12):4757-4766.

    • Author

    • McCormick JK, Poon A, Sailer M, Gao Y, Roy KL, McMullen LM, Vederas JC, Stiles ME, Van Belkum MJ.