General Information
-
DRAMP ID
- DRAMP00159
-
Peptide Name
- Lactocin 705beta (lac705beta; chain b of Lactocin 705; Bacteriocin)
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Source
- Lactobacillus casei CRL 705 (Gram-positive bacteria)
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Family
- Belongs to the class IIb bacteriocin
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Gene
- Not found
-
Sequence
- GFWGGLGYIAGRVGAAYGHAQASANNHHSPING
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Sequence Length
- 33
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
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Target Organism
- Several lactic acid bacteria, Listeria, Streptococci, etc.
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP00159.
Physicochemical Information
-
Formula
- C147H211N47O42
Absent Amino Acids
- CDEKMT
Common Amino Acids
- G
Mass
- 3308.58
PI
- 8.61
Basic Residues
- 4
Acidic Residues
- 0
Hydrophobic Residues
- 12
Net Charge
- +4
-
Boman Index
- -18.95
Hydrophobicity
- -0.224
Aliphatic Index
- 62.42
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 8480
Absorbance 280nm
- 265
Polar Residues
- 15
DRAMP00159
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Identification and nucleotide sequence of genes involved in the synthesis of lactocin 705, a two-peptide bacteriocin from Lactobacillus casei CRL 705.
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Pubmed ID
- 10754241
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Reference
- FEMS Microbiol Lett. 2000 Apr 15;185(2):157-161.
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Author
- Cuozzo SA, Sesma F, Palacios JM, de Ruz Holgado AP, Raya RR.