• DRAMP ID

    • DRAMP00178
    • Peptide Name

    • Enterocin EJ97 (EntEJ97; Bacteriocin)
    • Source

    • Enterococcus faecalis EJ97 (Gram-positive bacteria)
    • Family

    • Belongs to the class IId bacteriocin
    • Gene

    • ej97a
    • Sequence

    • MLAKIKAMIKKFPNPYTLAAKLTTYEINWYKQQYGRYPWERPVA
    • Sequence Length

    • 44
    • Evidence code

    • Predicted
    • Biological Activity

    • Antibacterial, Anti-Gram+, Antimicrobial
    • Target Organism

      • Gram-positive bacteria: Bacillus circulans (MIC=12 µg/ml), Bacillus coagulans CECT 12 (MIC=2 µg/ml), Bacillus megaterium (MIC=4 µg/ml), Bacillus stearothermophilus CECT 49 (MIC=14 µg/ml), Bacillus stearothermophilus CECT 148 (MIC=12 µg/ml), Bacillus subtilis (MIC=12 µg/ml), Paenibacillus macerans CECT 19 (MIC=4 µg/ml), Enterococcus faecalis ssp.faecalis S-13 (MIC=6 µg/ml), E. faecalis ssp.faecalis S-14 (MIC=8 µg/ml), E. faecalis ssp.faecalis S-32 (MIC=12 µg/ml), E. faecalis ssp.faecalis S-86 (MIC=8 µg/ml), E. faecalis ssp.liquefaciens S-39 (MIC=6 µg/ml), E. faecalis ssp.liquefaciens S-40 (MIC=8 µg/ml), E. faecalis ssp. liquefaciens S-47 (MIC=12 µg/ml).
    • Hemolytic activity

    • Unknown
    • Binding Target

    • Unknown
    • Formula

    • C252H384N62O61S2
    • Absent Amino Acids

    • CDHS
    • Common Amino Acids

    • K
    • Mass

    • 6089.48
    • PI

    • 10.39
    • Basic Residues

    • 8
    • Acidic Residues

    • 2
    • Hydrophobic Residues

    • 15
    • Boman Index

    • -53.64
    • Hydrophobicity

    • -58.86
    • Aliphatic Index

    • 71.14
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 18450
    • Absorbance 280nm

    • 429.07
    • Polar Residues

    • 11

DRAMP00178

DRAMP00178 chydropathy plot
    • No comments found on DRAMP database

  • Literature 1
    • Reference

    • Appl Environ Microbiol. 2003 Mar;69(3):1633-1641.
    • Author

    • S¡nchez-Hidalgo M, Maqueda M, G¡lvez A, Abriouel H, Valdivia E, Mart­nez-Bueno M.
    • Title

    • The genes coding for enterocin EJ97 production by Enterococcus faecalis EJ97 are located on a conjugative plasmid.
  • Literature 2
    • Reference

    • Protein Eng Des Sel. 2010 Jul;23(7):507-518.
    • Author

    • Neira JL, Contreras LM, de los Pa±os OR, S¡nchez-Hidalgo M, Mart­nez-Bueno M, Maqueda M, Rico M.
    • Title

    • Structural characterisation of the natively unfolded enterocin EJ97.
  • Literature 3
    • Reference

    • Arch Microbiol. 1998 Dec;171(1):59-65.
    • Author

    • G¡lvez A, Valdivia E, Abriouel H, Camafeita E, Mendez E, Mart­nez-Bueno M, Maqueda M.
    • Title

    • Isolation and characterization of enterocin EJ97, a bacteriocin produced by Enterococcus faecalis EJ97.