• DRAMP ID

    • DRAMP00226
    • Peptide Name

    • Bioactive peptide 3 (BAP3; Curvalicin-28c; Bacteriocin)
    • Source

    • Lactobacillus curvatus (Gram-positive bacteria)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • NIPQLTPTP
    • Sequence Length

    • 9
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+
    • Target Organism

      • Gram-positive bacteria: Listeria monocytogenes, Lactococcus lactis subsp lactis and Lactobacillus curvatus H28.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP00226 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • Formula

    • C44H73N11O14
    • Absent Amino Acids

    • ACDEFGHKMRSVWY
    • Common Amino Acids

    • P
    • Mass

    • 980.13
    • PI

    • 5.52
    • Basic Residues

    • 0
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 2
    • Net Charge

    • 0
    • Boman Index

    • -7.48
    • Hydrophobicity

    • -0.544
    • Aliphatic Index

    • 86.67
    • Half Life

      • Mammalian:1.4 hour
      • Yeast:3 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 3

DRAMP00226

    • Function

    • Has antibacterial activity against the Gram-positive bacteria and the Gram-positive bacteria. Has no antifungal activity against S.cerevisiae, Penicillium sp BKS-TAN2 or A.niger.
    • PTM

    • Contains one disulfide bond.
  • ·Literature 1
    • Title

    • Production of three anti-listerial peptides by Lactobacillus curvatus in MRS broth.
    • Reference

    • Food Res. Intern. 2010;43:33-39.
    • Author

    • Ghalfi H, Benkerroum N, Ongena M, Bensaid M, Thonart P.