General Information
-
DRAMP ID
- DRAMP00226
-
Peptide Name
- Bioactive peptide 3 (BAP3; Curvalicin-28c; Bacteriocin)
-
Source
- Lactobacillus curvatus (Gram-positive bacteria)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- NIPQLTPTP
-
Sequence Length
- 9
-
UniProt Entry
- P84711
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+
-
Target Organism
-
- Gram-positive bacteria: Listeria monocytogenes, Lactococcus lactis subsp lactis and Lactobacillus curvatus H28.
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- Please click DRAMP00226_predicted_structure.pdb to download.
Physicochemical Information
-
Formula
- C44H73N11O14
Absent Amino Acids
- ACDEFGHKMRSVWY
Common Amino Acids
- P
Mass
- 980.13
PI
- 5.52
Basic Residues
- 0
Acidic Residues
- 0
Hydrophobic Residues
- 2
Net Charge
- 0
-
Boman Index
- -7.48
Hydrophobicity
- -0.544
Aliphatic Index
- 86.67
Half Life
-
- Mammalian:1.4 hour
- Yeast:3 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 3
DRAMP00226
Comments Information
Function
- Has antibacterial activity against the Gram-positive bacteria and the Gram-positive bacteria. Has no antifungal activity against S.cerevisiae, Penicillium sp BKS-TAN2 or A.niger.
PTM
- Contains one disulfide bond.
Literature Information
- ·Literature 1
-
Title
- Production of three anti-listerial peptides by Lactobacillus curvatus in MRS broth.
-
Pubmed ID
- PubMed ID is not available
-
Reference
- Food Res. Intern. 2010;43:33-39.
-
Author
- Ghalfi H, Benkerroum N, Ongena M, Bensaid M, Thonart P.