• DRAMP ID

    • DRAMP00227
    • Peptide Name

    • Bioactive peptide 2 (BAP2;Curvalicin-28b; Bacteriocin)
    • Source

    • Lactobacillus curvatus (Gram-positive bacteria)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • VAPFPEQFLX
    • Sequence Length

    • 10
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+
    • Target Organism

      • Gram-positive bacteria: Listeria monocytogenes, Lactococcus lactis subsp lactis and Lactobacillus curvatus H28.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP00227 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • Formula

    • C52H72N10O12
    • Absent Amino Acids

    • CDGHIKMNRSTWY
    • Common Amino Acids

    • FP
    • Mass

    • 1158.55
    • PI

    • 4
    • Basic Residues

    • 0
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 5
    • Net Charge

    • -1
    • Boman Index

    • 4.38
    • Hydrophobicity

    • 0.52
    • Aliphatic Index

    • 78
    • Half Life

      • Mammalian:100 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 0

DRAMP00227

    • Function

    • Has antibacterial activity. Has no antifungal activity against S. cerevisiae, Penicillium sp BKS-TAN2 or A. niger.
  • ·Literature 1
    • Title

    • Production of three anti-listerial peptides by Lactobacillus curvatus in MRS broth.
    • Reference

    • Food Res. Intern. 2010;43:33-39.
    • Author

    • Ghalfi H, Benkerroum N, Ongena M, Bensaid M, Thonart P.