General Information

    • DRAMP ID

    • DRAMP00233

    • Peptide Name

    • Lichenin (Bacteriocin-like)

    • Source

    • Bacillus licheniformis (Gram-positive bacteria)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • ISLEICXIFHDN

    • Sequence Length

    • 12

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00233 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00233.

Physicochemical Information

    • Formula

    • C58H88N14O17S

    • Absent Amino Acids

    • AGKMPQRTVWY

    • Common Amino Acids

    • I

    • Mass

    • 1414.83

    • PI

    • 4.35

    • Basic Residues

    • 1

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 5

    • Net Charge

    • -1

    • Boman Index

    • -6.29

    • Hydrophobicity

    • 0.675

    • Aliphatic Index

    • 130

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 3

DRAMP00233

Comments Information

    • Function

    • Residue A7 is uncertain. Has antibacterial activity only against strictly anaerobic rumen bacteria.

    • Biophysicochemical properties

    • pH dependence (Optimum pH is 6.8); Temperature dependence (Optimum temperature is 39 degrees Celsius).

Literature Information

  • ·Literature 1

    • Title

    • Purification and characterization of a bacteriocin-like compound (Lichenin) produced anaerobically by Bacillus licheniformis isolated from water buffalo.

    • Reference

    • J Appl Microbiol. 2001 Oct;91(4):636-645.

    • Author

    • Pattnaik P, Kaushik JK, Grover S, Batish VK.
  • ·Literature 2

    • Title

    • Effect of environmental factors on production of lichenin, a chromosomally encoded bacteriocin-like compound produced by Bacillus licheniformis 26L-10/3RA.

    • Reference

    • Microbiol Res. 2005;160(2):213-218.

    • Author

    • Pattnaik P, Grover S, Batish VK.