General Information

    • DRAMP ID

    • DRAMP00241

    • Peptide Name

    • Brevicin 27 (Bacteriocin)

    • Source

    • Lactobacillus brevis SB27 (Gram-positive bacteria)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • KKXXKKVAXTWGNAATAAASGAVKGILG

    • Sequence Length

    • 28

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00241 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00241.

Physicochemical Information

    • Formula

    • C107H178N32O27

    • Absent Amino Acids

    • CDEFHMPQRY

    • Common Amino Acids

    • A

    • Mass

    • 2732.83

    • PI

    • 10.6

    • Basic Residues

    • 5

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +5

    • Boman Index

    • -6.25

    • Hydrophobicity

    • 0.057

    • Aliphatic Index

    • 73.57

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 203.7

    • Polar Residues

    • 8

DRAMP00241

DRAMP00241 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Purification and partial amino acid sequence of brevicin 27, a bacteriocin produced by Lactobacillus brevis SB27.

    • Reference

    • Curr Microbiol. 1997 Mar;34(3):173-179.

    • Author

    • Benoit V, Lebrihi A, Milli¨re JB, Lefebvre G.