General Information
-
DRAMP ID
- DRAMP00242
-
Peptide Name
- Subpeptin JM4-B (Bacteriocin)
-
Source
- Bacillus subtilis JM4 (Gram-positive bacteria)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- XXKEIXHIFHDN
-
Sequence Length
- 12
-
UniProt Entry
- P83879
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+
-
Target Organism
-
- Gram-positive bacteria: Salmonella, Bacillus cereus, Bacillus megaterium, Lactobacillus casei, Leptostylus viridescens, Myotis flavus, Corynebacterium glutamicum, Corynebacterium crenatum, Leuconostoc mesenteroides, Enterococcus faecalis, Shigella flexneri, Staphylococcus aureus and Bacillus thuringiensis.
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00242.
Physicochemical Information
-
Formula
- C52H71N15O12
Absent Amino Acids
- ACGLMPQRSTVWY
Common Amino Acids
- X
Mass
- 1486.27
PI
- 5.99
Basic Residues
- 3
Acidic Residues
- 2
Hydrophobic Residues
- 3
Net Charge
- +1
-
Boman Index
- -24.22
Hydrophobicity
- -0.75
Aliphatic Index
- 65
Half Life
-
- Mammalian:?
- Yeast:?
- E.coli:?
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 1
DRAMP00242
Comments Information
Function
- Has antibacterial activity against Gram-positive and Gram-negative bacteria.
Developmental stage
- Expressed from the mid-exponential phase, maximum activity is reached at the stationary phase.
Literature Information
- ·Literature 1
-
Title
- Purification and characterization of two novel antimicrobial peptides Subpeptin JM4-A and Subpeptin JM4-B produced by Bacillus subtilis JM4.
-
Pubmed ID
- 16211432
-
Reference
- Curr Microbiol. 2005 Nov;51(5):292-296.
-
Author
- Wu S, Jia S, Sun D, Chen M, Chen X, Zhong J, Huan L.