• DRAMP ID

    • DRAMP00244
    • Peptide Name

    • Hominicin (Bacteriocin)
    • Source

    • Staphylococcus hominis MBBL 2-9 (Gram-positive bacteria)
    • Family

    • Unknown
    • Gene

    • Unknown
    • Sequence

    • XTPATPFTPAITEITAAVIAX
    • Sequence Length

    • 21
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknown
    • Biological Activity

    • Antibacterial, Anti-Gram+, Antimicrobial
    • Target Organism

      • Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=0.06 µg/ml), S. aureus ATCC (MRSA) 11435 (MIC=0.96 µg/ml), S. aureus (vancomycin-intermediate VISA) CCARM 3501 (MIC=3.82 µg/ml).
    • Hemolytic activity

    • Unknown
    • Binding Target

    • Unknown
    • Structure

    • Unknown
    • Structure Description

    • Unknown
    • DRAMP00244 helical wheel diagram
    • Formula

    • C87H137N19O25
    • Absent Amino Acids

    • CDGHKLMNQRSWY
    • Common Amino Acids

    • AT
    • Mass

    • 2426.08
    • PI

    • 3.85
    • Basic Residues

    • 0
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 10
    • Boman Index

    • 11.17
    • Hydrophobicity

    • 84.29
    • Aliphatic Index

    • 93.33
    • Half Life

      • Mammalian:?
      • Yeast:?
      • E.coli:?
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 5

DRAMP00244

DRAMP00244 chydropathy plot
    • Hominicin exhibited heat stability up to 121 degrees C for 15min and activity under both acidic and basic conditions (from pH 2.0 to 10.0).

  • Literature 1
    • Reference

    • Biochem Biophys Res Commun. 2010 Aug 20;399(2):133-138.
    • Author

    • Kim PI, Sohng JK, Sung C, Joo HS, Kim EM, Yamaguchi T, Park D, Kim BG.
    • Title

    • Characterization and structure identification of an antimicrobial peptide, hominicin, produced by Staphylococcus hominis MBBL 2-9.