General Information
-
DRAMP ID
- DRAMP00246
-
Peptide Name
- Gramicidin B (GB; Bacteriocin)
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Source
- Bacillus brevis (soil bacterium) (Gram-positive bacteria)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- VGALAVVVWLFLWLW
-
Sequence Length
- 15
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antbacterial, Antiviral
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Beta strand (1 strands; 13 residues)
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- 1JO3 resolved by NMR.
- 1JO3-> 
-
Predicted Structure
- There is no predicted structure for DRAMP00246.
Physicochemical Information
-
Formula
- C94H134N18O16
Absent Amino Acids
- CDEHIKMNPQRSTY
Common Amino Acids
- LV
Mass
- 1772.21
PI
- 5.49
Basic Residues
- 0
Acidic Residues
- 0
Hydrophobic Residues
- 14
Net Charge
- 0
-
Boman Index
- 50.37
Hydrophobicity
- 2.353
Aliphatic Index
- 194.67
Half Life
-
- Mammalian:100 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 16500
Absorbance 280nm
- 1178.57
Polar Residues
- 1
DRAMP00246
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Structures of gramicidins A, B, and C incorporated into sodium dodecyl sulfate micelles.
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Pubmed ID
- 11570868
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Reference
- Biochemistry 2001; 40: 11676-11686.
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Author
- Townsley, L.E, Tucker, W.A, Sham, S, Hinton, J.F.