General Information

    • DRAMP ID

    • DRAMP00249

    • Peptide Name

    • Pln149 (Plantaricin 149; Bacteriocin; Derivatives: Pln149a)

    • Source

    • Lactobacillus plantarum NRIC 149 (Gram-positive bacteria)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • YSLQMGATAIKQVKKLFKKKGG

    • Sequence Length

    • 22

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Cell membrance

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Alpha helix

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00249 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00249.

Physicochemical Information

    • Formula

    • C111H190N30O28S

    • Absent Amino Acids

    • CDEHNPRW

    • Common Amino Acids

    • K

    • Mass

    • 2424.97

    • PI

    • 10.4

    • Basic Residues

    • 6

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 7

    • Net Charge

    • +6

    • Boman Index

    • -19.92

    • Hydrophobicity

    • -0.446

    • Aliphatic Index

    • 75.45

    • Half Life

      • Mammalian:2.8 hour
      • Yeast:10 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 70.95

    • Polar Residues

    • 6

DRAMP00249

DRAMP00249 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Plantaricin-149, a bacteriocin produced by Lactobacillus plantarum NRIC 149.

    • Reference

    • J. Fermentation Bioeng. 1994;77(3):277-282.

    • Author

    • Kato T, Matsuda T, Ogawa E, Ogawa H, Kato H, Doi U.