General Information

    • DRAMP ID

    • DRAMP00264

    • Peptide Name

    • Coconut antifungal peptide (Plants)

    • Source

    • Cocos nucifera

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • EQCREEEDDR

    • Sequence Length

    • 10

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal, Antiviral

    • Target Organism

      • Fungi: Fusarium oxysporum, Mycosphaerella arachidicola (IC50=1.2 µM), Physalospora piricola.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00264 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00264.

Physicochemical Information

    • Formula

    • C48H77N17O24S

    • Absent Amino Acids

    • AFGHIKLMNPSTVWY

    • Common Amino Acids

    • E

    • Mass

    • 1308.3

    • PI

    • 4.08

    • Basic Residues

    • 2

    • Acidic Residues

    • 6

    • Hydrophobic Residues

    • 0

    • Net Charge

    • -4

    • Boman Index

    • -78.78

    • Hydrophobicity

    • -3.1

    • Aliphatic Index

    • 0

    • Half Life

      • Mammalian:1 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 1

DRAMP00264

Comments Information

    • Function

    • Also has HIV-1 reverse transcriptase activity (IC50=52.5 µM)

Literature Information

  • ·Literature 1

    • Title

    • An antifungal peptide from the coconut.

    • Reference

    • Peptides. 2005 Dec;26(12):2392-2396.

    • Author

    • Wang HX, Ng TB.